锦鲤求职岗位描述
岗位职责
3. Develop LC-UV-MS and/or LC/radio detection/MS methods for detection, identification and semi-quantitative analysis of metabolites. Mass balance experience is preferred.
开发LC-UV-MS和/或LC/radio detection/MS方法，用于检测、鉴定和半定量分析代谢物。物质平衡的经验优先考虑。
4. Conduct metabolite detection, characterization experiments in liver microsomes, S9 fraction, hepatocytes, plasma, urine, bile and tissues.
在肝微粒体、S9组分、肝细胞、血浆、尿液、胆汁和组织中进行代谢物检测、表征实验。
5. Provide data interpretation and generate metabolite profiling and identification reports for various drug metabolism and ADME studies.
为各种药物代谢和ADME研究提供数据解释并生成代谢物分析和鉴定报告。
6. Generate study protocols for in vitro metabolism and in vivo ADME experiments based on needs for drug discovery, development and regulatory registration.
根据药物发现、开发和监管注册的需要，生成体外代谢和体内ADME实验的研究方案。
7. Familiar with study related guidelines, SOPs, protocols and technical reports. Respond to client’s questions or QC findings timely to ensure the study are completed within the planned time frame.
熟悉项目相关的法规、SOPs、方案和技术报告。及时解答客户的疑问，QC相关的发现项，确保项目在计划的时间表内完成。
8. Assist in instrument maintenance to support the project need.
协助维护仪器设备，以满足项目的检测需求。
9. Complying with EH&S policy. Maintain tidy in their workplace; Use personal protective equipment properly.
遵守安全守则。维持工作区域的清洁。试验中合理的使用个人防护设备。
岗位要求
药物代谢、药代动力学、有机化学等相关领域博士或硕士学位，3-5年相关工作经验。药物代谢、酶学和/或小分子和大分子结构阐明方面的工作知识。具有使用和维护液相色谱-高分辨质谱的实际经验，用于生物样品中小分子和大分子检测和结构表征。良好的英语口语和写作技巧。